SpaceX launches Ax-4 mission to the ISS with international crew

SpaceX launched the Falcon 9 rocket kickstarting Axiom Space’s Ax-4 mission to the International Space Station (ISS). Axiom’s Ax-4 mission is led by a historic international crew and lifted off from Kennedy Space Center’s Launch Complex 39A at 2:31 a.m. ET on June 25, 2025.

The Ax-4 crew is set to dock with the ISS around 7 a.m. ET on Thursday, June 26, 2025. Axiom Space, a Houston-based commercial space company, coordinated the mission with SpaceX for transportation and NASA for ISS access, with support from the European Space Agency and the astronauts’ governments.

The Ax-4 mission marks a milestone in global space collaboration. The Ax-4 crew, commanded by U.S. astronaut Peggy Whitson, includes Shubhanshu Shukla from India as the pilot, alongside mission specialists Sławosz Uznański-Wiśniewski from Poland and Tibor Kapu from Hungary.

“The trip marks the return to human spaceflight for those countries — their first government-sponsored flights in more than 40 years,” Axiom noted.

Shukla’s participation aligns with India’s Gaganyaan program planned for 2027. He is the first Indian astronaut to visit the ISS since Rakesh Sharma in 1984.

Axiom’s Ax-4 mission marks SpaceX’s 18th human spaceflight. The mission employs a Crew Dragon capsule atop a Falcon 9 rocket, designed with a launch escape system and “two-fault tolerant” for enhanced safety. The Axiom mission faced a few delays due to weather, a Falcon 9 leak, and an ISS Zvezda module leak investigation by NASA and Roscosmos before the recent successful launch.

As the crew prepares to execute its scientific objectives, SpaceX’s Ax-4 mission paves the way for a new era of inclusive space research, inspiring future generations and solidifying collaborative ties in the cosmos. During the Ax-4 crew’s 14-day stay in the ISS, the astronauts will conduct nearly 60 experiments.

“We’ll be conducting research that spans biology, material, and physical sciences as well as technology demonstrations,” said Whitson. “We’ll also be engaging with students around the world, sharing our experience and inspiring the next generation of explorers.”

SpaceX’s Ax-4 mission highlights Axiom’s role in advancing commercial spaceflight and fostering international partnerships. The mission strengthens global space exploration efforts by enabling historic spaceflight returns for India, Poland, and Hungary.

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